URGENT UPDATE: New research from Sylvester Cancer Institute reveals alarming links between breast cancer and living near federally designated Superfund sites. The findings, particularly concerning aggressive forms of breast cancer, are being released as October 2025 marks Breast Cancer Awareness Month.
Women residing near these hazardous waste sites are at a significantly higher risk of developing aggressive breast cancer subtypes, including the challenging triple-negative breast cancer. This urgent revelation underscores the critical need for environmental health assessments and immediate public awareness.
Additionally, Sylvester Cancer Institute will co-lead a groundbreaking $16 million national study to explore the potential of artificial intelligence (AI) in enhancing mammogram interpretations. The initiative, known as the PRISM Trial (Pragmatic Randomized Trial of Artificial Intelligence for Screening Mammography), will involve hundreds of thousands of mammograms across multiple states, including Florida, California, Massachusetts, Washington, and Wisconsin.
The study aims to determine if AI can assist radiologists in providing more accurate diagnoses, potentially revolutionizing breast cancer screening and early detection methods.
In a related study, researchers have discovered that glioblastoma cells that “unstick” from their clusters become more lethal. This finding provides new insights into tumor behavior and could pave the way for advanced treatment strategies. Dr. Anna Lasorella, co-director of the Sylvester Brain Tumor Institute, emphasized the importance of understanding glioblastoma biology for future research.
The implications of these studies extend to blood cancer as well. A recent investigation into multiple myeloma has mapped the timeline of DNA damage leading to this prevalent blood cancer, which could significantly enhance patient treatment strategies. Dr. C. Ola Landgren, a study author, highlighted the necessity of defining biological subtypes for effective precision medicine.
Another noteworthy study evaluated the effectiveness of AI-powered medical advice for blood cancer. Researchers found that while AI tools like ChatGPT perform well with general inquiries, they often fall short on specific treatment information. Dr. Justin Taylor cautioned patients to remain skeptical and consult their doctors for critical medical advice.
Moreover, researchers at Sylvester have received a $2.4 million grant from the National Cancer Institute to further explore the role of the protein GAK in diffuse large B-cell lymphoma (DLBCL), the most common form of blood cancer. This project aims to uncover new treatment possibilities by targeting GAK.
In a significant advancement for patient care, a trial revealed that remote perioperative monitoring (RPM) can lead to faster recovery and fewer complications following cancer surgery. This innovative approach was compared to traditional care methods among nearly 300 patients, emphasizing the critical recovery phase post-surgery.
Lastly, in leadership news, Dr. Mikkael Sekeres, chief of the Division of Hematology at Sylvester, has been elected to the executive committee of the American Society of Hematology, a major milestone in his career that will commence after the 2025 ASH Annual Meeting in Orlando, Florida from December 6-9.
These developments highlight the urgent need for heightened awareness and research investment in cancer treatment and prevention strategies. With new findings emerging, the health community and patients alike are encouraged to stay informed and proactive.
